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    NONSENSE MUTATION CORRECTION IN HUMAN DISEASES-AN APPROACH FOR TARGETED MEDICINE
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    786084

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    Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).

    It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.
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    ISBN9780128044681
    Peso212g
    Livro disponível - pronta entregaNão
    IdiomaInglês
    Tipo itemLIVRO IMPORTADO ADQ MERC INTERNO
    Número de páginas190
    Número da edição1ª EDIÇÃO - 2016
    Código Interno786084
    Código de barras9780128044681
    AcabamentoPAPERBACK
    AutorLEJEUNE, FABRICE
    EditoraACADEMIC PRESS
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