CARDIAC MECHANO-ELECTRIC FEEDBACK AND ARRHYTHMIAS

Kohl (Cardio Mechano-Electric Feedback Lab, Oxford University) documents the role of mechano-electric feedback (Mef) in electrical and mechanical pathological remodeling of cardiac function. Sections cover sub-cellular mechanisms of cardiac Mef, effects of Mef on cardiac cellular electrophysiology, experimental manifestations of Mef in the heart, cardiac Mef in normal physiology, cardiac Mef as a pathogenic mechanism, Mef as a mechanism involved in therapeutic interventions, and the outlook for the future. B&w and color photos and medical images are included.