This is one of three books in a collection covering all aspects of distillation. Distillation is the oldest technology available for the separation and purification of liquid mixtures and is a key unit operation within the petroleum refining, chemical, petrochemical, pharmaceutical, food, and alcohol industries. Distillation: Operation and Applications provides an overview on all operational aspects and describes application technologies. The first part describes control and operation principles of columns including coupled and heat integrated columns, explains troubleshooting analysis, and outlines performance testing techniques for industrial scale columns with all types of internals. The following parts describe in detail the different configurations of distillation sequences used in refineries including the choice of column internals, in big scale plants for bulk chemicals with respect to typical performance factors like foaming, wetting, or fouling. In addition, the book describes the special aspects of distillation in smaller scale plants for specialty chemicals that frequently need low pressure conditions and introduces the very special application of air distillation. A further focus is on novel techniques like HiGee equipment and micro distillation. The book presents new application fields for distillation in biotechnology, especially with respect to the different demands connected with red, green, and white biotechnology. The last part explains the application fields of new separating agents like ionic liquids and hyperbranched polymers.